Lessons from mapping cancer information from European hospitals to ICD-O-3 conditions in OMOP

June 25, 2025

2024
OHDSI Global Symposium

Lars Halvorsena, Olivier Bouissoub, Elisabeth Rossb, Stelios Theophanousc, Joëlle Thonnardd, Piers Mahone [a] edenceHealth NV, Kontich, Belgium, [b] Oslo University Hospital, Oslo, Norway, [c] Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, [d] Clinique universitaires Saint-Luc, Brussels, Belgium, [e] IQVIA, London, UK

European hospitals in the DigiONE network1 are converting their cancer data to the OMOP common data model (CDM) and face a recurring conversion challenge in mapping cancer conditions.

The three hospitals have different paths for their mappings to ICD-O-3 condition concepts, and therefore undertook somewhat different approaches:

Two different vocabulary versions were in use at the three hospitals at the time of the transformation toOMOP CDM. As there were no recorded changes to the included ICD-O-3 concepts between these two vocabulary versions, this has no impact on the comparisons here.

All three hospitals ended up with ICD-O-3 condition codes which do not exist in the OHDSI vocabularies yet. There were 119 such codes which appeared in at least two of the three hospitals; missing codes that appeared at only one hospital were excluded from the final list to censor possible invalid topography and morphology combinations. Of these missing codes, 53 have already been defined for inclusion in a futureOHDSI vocabulary release, while 66 of these codes had not yet been included. As a result, the DigiONE hospitals will further evaluate these findings and work with the Oncology WG – Vocabulary subgroup to include an additional set of ICD-O-3 condition codes considered as relevant. This would positively impact future studies within the DigiONE network and other OMOP CDM-based oncology research networks.

Abstract

OHDSI-Blog

OHDSI Global Symposium 2024, 23-Oct-2024

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